The cells in the transitional epithelium are pear-shaped or round, but as tissue is stretched, cells become flattened, giving the appearance of stratified squamous epithelium . Transitional epithelia are made of 3-4 layers of cells with the lowermost or basal layer staying in contact with the basement membrane. These are among the least differentiated cells in this tissue and support the remaining cells. when the bladder is filled with urine), the tissue compresses and the cells become stretc… Structure of Transitional Epithelium: The transitional epithelium is composed of 3-4 layers of cells in which the lowermost or basal layer stays in contact with the basement membrane. Cells of the basal layer are cuboidal, or cube-shaped, and columnar, or column-shaped, while the cells of the superficial layer vary in appearance depending on the degree of distension. The appearance of transitional epithelium depends on the layers in which it resides. Structure of Transitional Epithelium. Structure of the transitional epithelium Transitional epithelium is an epithelial tissue which in a relaxed state appears as a stratified cuboidal epithelium . The cells on the basal layer are attached with lamina propria by tonofilaments and Hemi desmosomes. The cells of this basal layer are attached to the lamina propria through tonofilaments and hemi-desmosomes. These cells appear to be cuboidal with a domed apex when the organ or the tube in which they reside is not stretched. When the organ or tube is stretched (e.g.

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